Intravenous protein-free pyrogen; a powerful fibrinolytic agent in man.

A diimmistration of a variety of noonfibrinolytic, noanenizymImatic substances imdluces fibrinmolvsis in moan. The most potent materials of this type known at present are purified protein-fre( pyrogenms. Their action after intravenous injection on the huiman fibrinolytic system, on some of its componemIts, and on the clotting system of 67 individuals has been studied. The possible therapeutic immplications are discussed of thninarked fibrinolysis.